Prognostic significance of saddle pulmonary embolism a post hoc analysis of the PROTECT cohort study
Winnifer Briceño a), Sara González a), Carmen Rodríguez a), Ana Castillo a), Ignacio Jara a), Laura Lago a), Edwin Yong a), Alfonso Muriel b), Álvaro Dubois-Silva c), Behnood Bikdeli d) f), Gema Díaz g), David Jiménez a) h) i)
a) Respiratory Department, Hospital Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain
b) Biostatistics Department, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, CIBERESP, Madrid, Spain
c) Hospital at Home Unit, Complexo Hospitalario Universitario de A Coruña (CHUAC), Servizo Galego de Saúde (SERGAS), A Coruña, Spain
d) Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
e) Center for Outcomes Research and Evaluation (CORE), Yale University School of Medicine. New Haven, CT, USA
f) Cardiovascular Research Foundation, New York, USA
g) Respiratory Department, Hospital Puerta de Hierro, Madrid, Spain
h) Medicine Department, Universidad de Alcalá, Madrid, Spain
i) CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain
Highlights
• We assessed the association between the presence of saddle PE and the risk of a complicated course in stable patients with PE.
• Saddle PE was infrequent but patients with saddle PE had a higher risk of a complicated course rate than those without saddle PE.
• The addition of saddle PE to the ESC risk model increased its ability for identification of the sickest stable patients with PE.